Dedee Pfeiffer, who is the younger sibling of Hollywood ultra-siren Michelle Pfeiffer, launched her acting career way back in with an appearance on an episode of the hit series Simon & Simon.3/5(7). Aug 04, · Dedee Pfeiffer (IMDb) is Michelle Pfeiffer's sister. Dedee also had a layout in Playboy, where you'll note that they inconsistently edited away some of her tattoos. (Part 2/2) Click on Thanks (below left) if you like this post. ImageBam and other hosts lose files over time. If you notice missing images in any of my posts, please send . May 06, · Michelle & Dedee Pfeiffer Sisters Michelle has been a major star most of her life with films like "Scarface", "Batman Returns" & "Dark Shadows" while Dedee's major credit was television's "Cybill" co-starring .